The antiproliferative effects of vitamin D on a breast tumour cell line persist despite knockdown of the vitamin D receptor gene, and variants resistant to these anti-proliferative effects do not show changes in known vitamin D signaling pathway genes.
Methods for quantifying cellcell contact often rely on global descriptors, such as overall cell density, but a new statistical model that accounts for local interactions, such as individual cell-cell distances, reduces noisy data and effectively describes contact inhibition effects.
A comparative evolutionary analysis of two mouse long noncoding RNA libraries reveals a much larger pool of noncoding RNAs remains yet to be discovered.
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